Most people — about 85% to 90% — are right-handed and have been in the majority since the Stone Age. This session will focus on the genetic, neurological, and cultural factors that influence handedness, our preference for using one hand over the other, and what can be inferred from that preference. We will examine when handedness emerges in children and age-related changes in hand dominance. Finally, we will review whether animals have a dominant hand and whether it is even necessary to have a hand (or a paw) to show a preference.